South Carolina

Welcome to the Palmetto state!

" The Nursing Licensure Compact (NLC) is an agreement between states that allows nurses to have one license but the ability to practice in other states that are part of the agreement.

Originally developed in 2000, in 2024 the license had grown to include at least 25 states. To help streamline the process for nurses the Enhanced Nursing Licensure Compact (eNLC) was implemented in 2018 and included standards for licensure which the originally compact license was lacking.

Each state needs a competent medical workforce to meet the needs of it’s citizens. However, the requirements for some health care professions are not the same in each state. That is why it is important to find out what is required of you as a future or current registered nurse before moving across state lines. Contact information is located at the bottom of this page.


South Carolina is a compact state. If you are moving to South Carolina or claiming it as your primary state of residence, you will need to apply for application by endorsement in order to use your license in South Carolina. General instructions are listed below.

Your license must be renewed every even numbered year on the 30th of April. License renewal cost is $75. Click here for more information.

Continuing Competency

Continuing competency requirements are as follows:

Click here for more details.

To view other options, click here to go to the Continuing Competency Requirements page.

This state requires nurses to hold current ACLS certification.

Contact Information

Web Address:

Physical Address

Synergy Business Park Kingstree Building 110 Centerview Drive, Suite 202 Columbia, SC 29210

Phone Number: 803.896.4550

Fax Number: 803.896.4515


Click here for Frequently Asked Questions.

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